Data Science in the News

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LLNL and BridgeBio announce trials for supercomputing-discovered cancer drug

June 6, 2024 - 
In a substantial milestone for supercomputing-aided drug design, LLNL and BridgeBio Oncology Therapeutics (BridgeBio) today announced clinical trials have begun for a first-in-class medication that targets specific genetic mutations implicated in many types of cancer. The development of the new drug—BBO-8520—is the result of collaboration among LLNL, BridgeBio and the National Cancer...

The Laboratory’s habit of innovation

June 4, 2024 - 
LLNL’s HPC and data science capabilities play a significant role in international science research and innovation, and Lab researchers have won 10 R&D 100 Awards in the Software–Services category in the past decade. The latest issue of Science & Technology Review features several award-winning projects, including ZFP and CANDLE: (1) ZFP introduces a new method of compressing large data sets...

Statistical framework synchronizes medical study data

June 3, 2024 - 
The risks and benefits of heart surgery, chemotherapy, vaccination, and other medical treatments can change based on the time of day they are administered. These variations arise in part due to changes in gene expression levels throughout the 24-hour day-night cycle, with around 50% of genes displaying oscillatory behavior. To evaluate new therapies, investigators study how a gene’s...

Machine learning optimizes high-power laser experiments

May 17, 2024 - 
Commercial fusion energy plants and advanced compact radiation sources may rely on high-intensity, high-repetition rate lasers, capable of firing multiple times per second, but humans could be a limiting factor in reacting to changes at these shot rates. Applying advanced computing to this problem, a team of international scientists from LLNL, Fraunhofer Institute for Laser Technology (ILT)...

GUIDE team develops approach to redesign antibodies against viral pandemics

May 8, 2024 - 
In a groundbreaking development for addressing future viral pandemics, a multi-institutional team involving LLNL researchers has successfully combined an AI-backed platform with supercomputing to redesign and restore the effectiveness of antibodies whose ability to fight viruses has been compromised by viral evolution. The team’s research is published in the journal Nature and showcases a...

Igniting scientific discovery with AI and supercomputing (VIDEO)

April 15, 2024 - 
LLNL’s fusion ignition breakthrough, more than 60 years in the making, was enabled by a combination of traditional fusion target design methods, high-performance computing (HPC), and AI techniques. The success of ignition marks a significant milestone in fusion energy research, and was facilitated in part by the precision simulations and rapid experimental data analysis only possible through...

Predicting climate change impacts on infrastructure (VIDEO)

Feb. 26, 2024 - 
At LLNL, electrical grid experts and climate scientists work together to bridge the gap between infrastructure and climate modeling. By taking weather variables such as wildfire, flooding, wind, and sunlight that directly impact the electrical grid into consideration, researchers can improve electrical grid model projections for a more stable future. In a new video, LLNL computer scientist...

Machine learning tool fills in the blanks for satellite light curves

Feb. 13, 2024 - 
When viewed from Earth, objects in space are seen at a specific brightness, called apparent magnitude. Over time, ground-based telescopes can track a specific object’s change in brightness. This time-dependent magnitude variation is known as an object’s light curve, and can allow astronomers to infer the object’s size, shape, material, location, and more. Monitoring the light curve of...

Conference paper illuminates neural image compression

Dec. 8, 2023 - 
An enduring question in machine learning (ML) concerns performance: How do we know if a model produces reliable results? The best models have explainable logic and can withstand data perturbations, but performance analysis tools and datasets that will help researchers meaningfully evaluate these models are scarce. A team from LLNL’s Center for Applied Scientific Computing (CASC) is teasing...

Data Days brings DOE labs together for discussions on data management and more

Nov. 9, 2023 - 
Data researchers, developers, data managers, and program managers from the DOE national laboratories visited LLNL on October 24–26 to discuss the latest in data management, sharing, and accessibility at the 2023 DOE Data Days (D3) workshop. Sponsored by the National Nuclear Security Administration’s (NNSA) Office of Defense Nuclear Nonproliferation and hosted annually by LLNL, the event...

Making machine learning safer for biomedicine

Aug. 15, 2023 - 
It’s hard to understate the impact machine learning will have on biomedicine. The ability to train computers to spot patterns by analyzing large, complex datasets is driving discoveries in heart disease, cancer, neurodegenerative diseases and more. For instance, Argonne National Laboratory (ANL) has used machine learning to aid cancer research and accelerate COVID-19 antiviral discovery. One...

High-performance computing, AI and cognitive simulation helped LLNL conquer fusion ignition

June 21, 2023 - 
For hundreds of LLNL scientists on the design, experimental, and modeling and simulation teams behind inertial confinement fusion (ICF) experiments at the National Ignition Facility, the results of the now-famous Dec. 5, 2022, ignition shot didn’t come as a complete surprise. The “crystal ball” that gave them increased pre-shot confidence in a breakthrough involved a combination of detailed...

Visionary report unveils ambitious roadmap to harness the power of AI in scientific discovery

June 12, 2023 - 
A new report, the product of a series of workshops held in 2022 under the guidance of the U.S. Department of Energy’s Office of Science and the National Nuclear Security Administration, lays out a comprehensive vision for the Office of Science and NNSA to expand their work in scientific use of AI by building on existing strengths in world-leading high performance computing systems and data...

Consulting service infuses Lab projects with data science expertise

June 5, 2023 - 
A key advantage of LLNL’s culture of multidisciplinary teamwork is that domain scientists don’t need to be experts in everything. Physicists, chemists, biologists, materials engineers, climate scientists, computer scientists, and other researchers regularly work alongside specialists in other fields to tackle challenging problems. The rise of Big Data across the Lab has led to a demand for...

Data science meets fusion (VIDEO)

May 30, 2023 - 
LLNL’s historic fusion ignition achievement on December 5, 2022, was the first experiment to ever achieve net energy gain from nuclear fusion. However, the experiment’s result was not actually that surprising. A team leveraging data science techniques developed and used a landmark system for teaching artificial intelligence (AI) to incorporate and better account for different variables and...

LLNL and SambaNova Systems announce additional AI hardware to support Lab’s cognitive simulation efforts

May 23, 2023 - 
LLNL and SambaNova Systems have announced the addition of a spatial data flow accelerator into the Livermore Computing Center, part of an effort to upgrade the Lab’s CogSim program. LLNL will integrate the new hardware to further investigate CogSim approaches combining AI with high-performance computing—and how deep neural network hardware architectures can accelerate traditional physics...

Patent applies machine learning to industrial control systems

May 8, 2023 - 
An industrial control system (ICS) is an automated network of devices that make up a complex industrial process. For example, a large-scale electrical grid may contain thousands of instruments, sensors, and controls that transfer and distribute power, along with computing systems that capture data transmitted across these devices. Monitoring the ICS network for new device connections, device...

Computing codes, simulations helped make ignition possible

April 6, 2023 - 
Harkening back to the genesis of LLNL’s inertial confinement fusion (ICF) program, codes have played an essential role in simulating the complex physical processes that take place in an ICF target and the facets of each experiment that must be nearly perfect. Many of these processes are too complicated, expensive, or even impossible to predict through experiments alone. With only a few...

Scientists develop model for more efficient simulations of protein interactions linked to cancer

March 28, 2023 - 
LLNL scientists have developed a theoretical model for more efficient molecular-level simulations of cell membranes and their lipid-protein interactions, part of a multi-institutional effort to better understand the behavior of cancer-causing membrane proteins. Developed under an ongoing collaboration by the Department of Energy and the National Cancer Institute (NCI) aimed at modeling cell...

Skywing: Open-source software aids collaborative autonomy applications

Jan. 25, 2023 - 
A new software developed at LLNL, and known as Skywing, provides domain scientists working to protect the nation’s critical infrastructure with a high-reliability, real-time software platform for collaborative autonomy applications. The U.S. modern critical infrastructure—from the electrical grid that sends power to homes to the pipelines that deliver water and natural gas and the railways...