The Center for Applied Scientific Computing (CASC) serves as LLNL’s window to the broader computer science, computational physics, applied mathematics, and data science research communities. Major thrust areas in CASC research include: (1) Increasing simulation fidelity by integrating multi-physics and multi-scale models, increasing resolution through advanced numerical methods and more efficient algorithms, and performing uncertainty quantification. (2) Creating computing tools and programming environments that will enable and support extreme-scale computing. (3) Creating tools to manipulate, analyze, and visualize massive data sets for both the physical sciences and intelligence community applications. Watch on YouTube.